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Dr. Lorias’ minimally invasive PLATINUM Procedure for Penis Enlargement, may use Artefill as one of the enlargement substances. Dr. Loria uses a proprietary mixture of fillers he personally developed. So what is Artefill exactly? Artefill is an injectable filler that is safe and long lasting. Artefill consists of a combination of microsphere enhanced collagen and lidocaine for comfort. Artefill was approved by the U.S. FDA in October 2006 and has since been safely used on tens of thousands of patients. What makes this filler unique and chosen by Dr. Loria is that the microspheres and/or silicone micro-droplets are not absorbed by the patient’s body, thus producing long lasting results. The tiny microspheres in Artefill are made of polymethylmethacrylate (PMMA), one of the most commonly used materials in medicine since the late 40’s.  The microspheres in Artefill remain intact at the injection site and provide structural support, making it a perfect filler for the PLATINUM Procedure.